Nonprofits in South Carolina

Nonprofits in South Carolina. Browse 29,070 public nonprofit profiles. Review organization identities, available filing years, and their complete CharitySense profiles.

Location refers to headquarters recorded in public sources, not an organization’s service area. Classification describes its reported category and does not assess its effectiveness.

Nonprofit profiles

  1. Open Hands Africa Inc

    EIN 271901521 · Headquarters: GREENVILLE, SC, USA · Human Services · Latest available filing year: 2016 · Primary form: IRS Form 990

  2. Open Heart Ministry of Olga Anischenko

    EIN 853108539 · Headquarters: Boiling Springs, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  3. Open Hearts Child Education Corporation

    EIN 991250037 · Headquarters: Greenville, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  4. Open Heavens and Graced God's Women of Prayer Praise and Worship Inc

    EIN 331288885 · Headquarters: LUGOFF, SC, US · Religion Related · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  5. Open Mind Inc

    EIN 474050906 · Headquarters: Mt Pleasant, SC, US · Education · Latest available filing year: 2018 · Primary form: IRS Form 990-N

  6. Open Your Eyes Inc

    EIN 351687365 · Headquarters: Pauline, SC, US · Diseases, Disorders & Medical Disciplines · Latest available filing year: 2017 · Primary form: IRS Form 990-N

  7. Openhands Outreach Center

    EIN 842528318 · Headquarters: Greenwood, SC, US · Youth Development · Latest available filing year: 2021 · Primary form: IRS Form 990-N

  8. Opening Doors Ministires

    EIN 842861717 · Headquarters: WEST COLUMBIA, SC, USA · Human Services · Latest available filing year: 2019 · Primary form: IRS Form 990-EZ

  9. Opening Doors Ministry

    EIN 853972090 · Headquarters: WEST COLUMBIA, SC, USA · Education · Latest available filing year: 2025 · Primary form: IRS Form 990-EZ

  10. Openings-sc

    EIN 824472094 · Headquarters: Columbia, SC, US · Religion Related · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  11. Openmind Fitness Foundation

    EIN 932177250 · Headquarters: PAWLEYS ISLAND, SC, USA · Mental Health & Crisis Intervention · Latest available filing year: 2024 · Primary form: IRS Form 990-EZ

  12. Opera - Centro De Familia Corp

    EIN 455480844 · Headquarters: Greenville, SC, US · Mental Health & Crisis Intervention · Latest available filing year: 2020 · Primary form: IRS Form 990-N

  13. Opera Experience Southeast

    EIN 455057552 · Headquarters: ROCK HILL, SC, US · Arts, Culture & Humanities · Latest available filing year: 2021 · Primary form: IRS Form 990-N

  14. Operation 127 Inc

    EIN 270986449 · Headquarters: HILTON HEAD ISLAND, SC, US · Youth Development · Latest available filing year: 2010 · Primary form: IRS Form 990-N

  15. Operation Andrew Ministries Inc

    EIN 570886039 · Headquarters: Greenville, SC, US · Housing & Shelter · Latest available filing year: 2016 · Primary form: IRS Form 990-N

  16. Operation Beachhead

    EIN 261753844 · Headquarters: Rock Hill, SC, US · Religion Related · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  17. Operation Bear Hug Inc

    EIN 201399937 · Headquarters: Greenville, SC, US · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  18. Operation Bless a Child Jesus Cares

    EIN 900763826 · Headquarters: Andrews, SC, US · Food, Agriculture & Nutrition · Latest available filing year: 2012 · Primary form: IRS Form 990-N

  19. Operation Care

    EIN 020630281 · Headquarters: ROCK HILL, SC, USA · Animal Related · Latest available filing year: 2024 · Primary form: IRS Form 990-EZ

  20. Operation Care Food Bank

    EIN 455373722 · Headquarters: Williamston, SC, USA · Food, Agriculture & Nutrition · Latest available filing year: 2024 · Primary form: IRS Form 990-EZ

  21. Operation Constellation

    EIN 472675574 · Headquarters: Greenville, SC, US · Religion Related · Latest available filing year: 2021 · Primary form: IRS Form 990-N

  22. Operation Deep Valor

    EIN 392193872 · Headquarters: SUMMERVILLE, SC, US · Public & Societal Benefit · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  23. Operation Enduring Honor Inc

    EIN 852108879 · Headquarters: Clinton, SC, US · Public & Societal Benefit · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  24. Operation Enduring Life

    EIN 993209879 · Headquarters: CHARLESTON, SC, USA · Unknown & Unclassified · Latest available filing year: 2024 · Primary form: IRS Form 990

  25. Operation English

    EIN 934213626 · Headquarters: Greenville, SC, USA · Education · Latest available filing year: 2025 · Primary form: IRS Form 990-EZ

  26. Operation Fallen Feather

    EIN 883892676 · Headquarters: EASLEY, SC, US · Public & Societal Benefit · Latest available filing year: 2023 · Primary form: IRS Form 990-N

  27. Operation Freedom Awareness - a Mission Against Human Trafficking

    EIN 471225128 · Headquarters: Greer, SC, US · Human Services · Latest available filing year: 2016 · Primary form: IRS Form 990-N

  28. Operation Grogl

    EIN 824453391 · Headquarters: Williamston, SC, US · Recreation & Sports · Latest available filing year: 2022 · Primary form: IRS Form 990-N

  29. Operation Heal Our Heroes Inc

    EIN 473274752 · Headquarters: Charleston, SC, USA · Public & Societal Benefit · Latest available filing year: 2025 · Primary form: IRS Form 990-EZ

  30. Operation Home Inc

    EIN 621745925 · Headquarters: NORTH CHARLESTON, SC, USA · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990

  31. Operation Hope and Hooves Inc

    EIN 823787853 · Headquarters: Fort Mill, SC, US · Recreation & Sports · Latest available filing year: 2020 · Primary form: IRS Form 990-N

  32. Operation Hope Community Programs Inc

    EIN 810956075 · Headquarters: Pageland, SC, US · Youth Development · Latest available filing year: 2023 · Primary form: IRS Form 990-N

  33. Operation Impact

    EIN 570949821 · Headquarters: abbeville, SC, US · Philanthropy, Voluntarism & Grantmaking Foundations · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  34. Operation Keep Piggies Safe Sanctuary Inc

    EIN 834414777 · Headquarters: Kershaw, SC, US · Animal Related · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  35. Operation Leadership

    EIN 571093949 · Headquarters: Summerville, SC, US · Education · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  36. Operation Military Stress Relief Dolls Inc

    EIN 260464273 · Headquarters: WEST COLUMBIA, SC, USA · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990-EZ

  37. Operation North Star

    EIN 334789629 · Headquarters: WHITE ROCK, SC, US · International, Foreign Affairs & National Security · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  38. Operation Patriots Fob Inc

    EIN 850894599 · Headquarters: BLUFFTON, SC, USA · Philanthropy, Voluntarism & Grantmaking Foundations · Latest available filing year: 2025 · Primary form: IRS Form 990

  39. Operation Pride with Common Sense Ministries Inc

    EIN 843018151 · Headquarters: clemson, SC, US · Education · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  40. Operation Project Safe House

    EIN 394258920 · Headquarters: Mullins, SC, US · Community Improvement & Capacity Building · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  41. Operation Rehabilitation

    EIN 842981196 · Headquarters: Greenville, SC, USA · Public & Societal Benefit · Latest available filing year: 2025 · Primary form: IRS Form 990

  42. Operation Rest and Relax USA

    EIN 452219956 · Headquarters: HILTON HEAD, SC, USA · Human Services · Latest available filing year: 2019 · Primary form: IRS Form 990-EZ

  43. Operation Restoration

    EIN 570953101 · Headquarters: SPARTANBURG, SC, USA · Community Improvement & Capacity Building · Latest available filing year: 2024 · Primary form: IRS Form 990-EZ

  44. Operation Rise Again

    EIN 862042378 · Headquarters: MOUNT PLEASANT, SC, USA · Mental Health & Crisis Intervention · Latest available filing year: 2024 · Primary form: IRS Form 990-PF

  45. Operation Rudolph Inc

    EIN 571091602 · Headquarters: KERSHAW, SC, USA · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990-EZ

  46. Operation Santa Sc Inc

    EIN 454816407 · Headquarters: Greer, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  47. Operation Save the Day

    EIN 993862277 · Headquarters: Latta, SC, USA · Community Improvement & Capacity Building · Latest available filing year: 2025 · Primary form: IRS Form 990-EZ

  48. Operation Saving Jake Inc

    EIN 461796473 · Headquarters: Port Royal, SC, US · Human Services · Latest available filing year: 2014 · Primary form: IRS Form 990-N

  49. Operation Sight

    EIN 453449443 · Headquarters: MT PLEASANT, SC, USA · Diseases, Disorders & Medical Disciplines · Latest available filing year: 2024 · Primary form: IRS Form 990

  50. Operation Soldier Elf

    EIN 884183305 · Headquarters: GREENWOOD, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  51. Operation Thank You Inc

    EIN 550796469 · Headquarters: West Columbia, SC, US · Religion Related · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  52. Operation Turbo Inc

    EIN 471283265 · Headquarters: Hilton Head Island, SC, USA · Public & Societal Benefit · Latest available filing year: 2025 · Primary form: IRS Form 990-EZ

  53. Operation Turn Around

    EIN 263156057 · Headquarters: Greenville, SC, US · Mental Health & Crisis Intervention · Latest available filing year: 2009 · Primary form: IRS Form 990-N

  54. Operation Up

    EIN 844885672 · Headquarters: Florence, SC, US · Unknown & Unclassified · Latest available filing year: 2020 · Primary form: IRS Form 990-N

  55. Operation Vet Fit Inc

    EIN 460672516 · Headquarters: MOUNT PLEASANT, SC, USA · Public & Societal Benefit · Latest available filing year: 2025 · Primary form: IRS Form 990

  56. Operation Veteran Reintegration Inc

    EIN 842876704 · Headquarters: MYRTLE BEACH, SC, USA · Public & Societal Benefit · Latest available filing year: 2022 · Primary form: IRS Form 990-EZ

  57. Operation Veteran Support

    EIN 462923507 · Headquarters: Columbia, SC, US · Public Safety, Disaster Preparedness & Relief · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  58. Operation Veterans Relief

    EIN 463246922 · Headquarters: Summerville, SC, US · Public & Societal Benefit · Latest available filing year: 2019 · Primary form: IRS Form 990-N

  59. Ophelia & Jasper Ferguson Outreach Foundation Inc

    EIN 861382941 · Headquarters: Cayce, SC, US · Philanthropy, Voluntarism & Grantmaking Foundations · Latest available filing year: 2022 · Primary form: IRS Form 990-N

  60. Opia Arts Inc

    EIN 844439279 · Headquarters: Greenville, SC, US · Arts, Culture & Humanities · Latest available filing year: 2021 · Primary form: IRS Form 990-N

  61. Opportunity Drive

    EIN 843791345 · Headquarters: FORT MILL, SC, USA · Community Improvement & Capacity Building · Latest available filing year: 2022 · Primary form: IRS Form 990-EZ

  62. Opportunity for Change

    EIN 872139212 · Headquarters: Rock Hill, SC, US · Education · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  63. Opportunity Hub

    EIN 061644643 · Headquarters: SPARTANBURG, SC, USA · Food, Agriculture & Nutrition · Latest available filing year: 2023 · Primary form: IRS Form 990

  64. Opportunity South Carolina

    EIN 850901332 · Headquarters: GREENVILLE, SC, USA · Community Improvement & Capacity Building · Latest available filing year: 2024 · Primary form: IRS Form 990

  65. Optimal Soul Foundation

    EIN 920938732 · Headquarters: Greenville, SC, US · Health Care · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  66. Optimism Preventive Services Inc

    EIN 272204042 · Headquarters: Georgetown, SC, US · Crime & Legal Related · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  67. Optimist International

    EIN 237011662 · Headquarters: North Augusta, SC, US · Unknown & Unclassified · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  68. Optimist International

    EIN 237073261 · Headquarters: Florence, SC, US · Youth Development · Latest available filing year: 2018 · Primary form: IRS Form 990-N

  69. Optimist International

    EIN 465056454 · Headquarters: Rock Hill, SC, US · Education · Latest available filing year: 2018 · Primary form: IRS Form 990-N

  70. Optimist International

    EIN 474427594 · Headquarters: Murrells Inlet, SC, US · Youth Development · Latest available filing year: 2018 · Primary form: IRS Form 990-N

  71. Optimist International

    EIN 570743537 · Headquarters: BLYTHEWOOD, SC, US · Youth Development · Latest available filing year: 2012 · Primary form: IRS Form 990-N

  72. Optimist International

    EIN 570782859 · Headquarters: ROCK HILL, SC, US · Unknown & Unclassified · Latest available filing year: 2022 · Primary form: IRS Form 990-N

  73. Optimist International

    EIN 570786917 · Headquarters: myrtle beach, SC, US · Unknown & Unclassified · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  74. Optimist International

    EIN 570912411 · Headquarters: Chester, SC, US · Youth Development · Latest available filing year: 2017 · Primary form: IRS Form 990-N

  75. Optimist International

    EIN 570984760 · Headquarters: Chapin, SC, US · Youth Development · Latest available filing year: 2014 · Primary form: IRS Form 990-N

  76. Optimist International

    EIN 576025048 · Headquarters: Charleston, SC, US · Youth Development · Latest available filing year: 2008 · Primary form: IRS Form 990-N

  77. Optimist International

    EIN 576025054 · Headquarters: Rock Hill, SC, US · Unknown & Unclassified · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  78. Optimist International

    EIN 576025213 · Headquarters: Spartanburg, SC, US · Unknown & Unclassified · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  79. Optimist International

    EIN 576025400 · Headquarters: Columbia, SC, US · Youth Development · Latest available filing year: 2007 · Primary form: IRS Form 990-N

  80. Optimist International

    EIN 576027111 · Headquarters: Sumter, SC, US · Unknown & Unclassified · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  81. Optimist International

    EIN 576028365 · Headquarters: Charleston, SC, US · Unknown & Unclassified · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  82. Optimist International

    EIN 576029186 · Headquarters: columbia, SC, US · Youth Development · Latest available filing year: 2008 · Primary form: IRS Form 990-N

  83. Optimist International

    EIN 576036540 · Headquarters: Lugoff, SC, US · Unknown & Unclassified · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  84. Optimist International

    EIN 576036753 · Headquarters: Hollywood, SC, US · Youth Development · Latest available filing year: 2011 · Primary form: IRS Form 990-N

  85. Optimist International

    EIN 812574907 · Headquarters: Sumter, SC, US · Unknown & Unclassified · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  86. Optimist International

    EIN 814359494 · Headquarters: myrtle beach, SC, US · Unknown & Unclassified · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  87. Optimist International

    EIN 821523700 · Headquarters: Sumter, SC, US · Unknown & Unclassified · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  88. Optimist International

    EIN 900249326 · Headquarters: Clover, SC, US · Youth Development · Latest available filing year: 2008 · Primary form: IRS Form 990-N

  89. Optimist International

    EIN 900765324 · Headquarters: Rock Hill, SC, US · Unknown & Unclassified · Latest available filing year: 2015 · Primary form: IRS Form 990-N

  90. Optimist International

    EIN 901019141 · Headquarters: Pawleys Island, SC, US · Youth Development · Latest available filing year: 2016 · Primary form: IRS Form 990-N

  91. Optimist International

    EIN 911866106 · Headquarters: Sumter, SC, US · Unknown & Unclassified · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  92. Optimist International 22155 Oc of St Andrews Sc

    EIN 237156333 · Headquarters: COLUMBIA, SC, USA · Unknown & Unclassified · Latest available filing year: 2024 · Primary form: IRS Form 990-EZ

  93. Optus Community Capital

    EIN 884417477 · Headquarters: COLUMBIA, SC, US · Community Improvement & Capacity Building · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  94. Opus Independent Winter Guard Inc

    EIN 993338283 · Headquarters: Clover, SC, US · Arts, Culture & Humanities · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  95. Opwa-okigwe Provincial World Assembly

    EIN 845063783 · Headquarters: Sumter, SC, US · Education · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  96. Orange Crush Baseball

    EIN 270129146 · Headquarters: Charleston, SC, US · Recreation & Sports · Latest available filing year: 2009 · Primary form: IRS Form 990-N

  97. Orange Grove Charter School

    EIN 202490360 · Headquarters: CHARLESTON, SC, USA · Education · Latest available filing year: 2024 · Primary form: IRS Form 990

  98. Orange Grove Elementary Charter School Pto

    EIN 262148527 · Headquarters: CHARLESTON, SC, USA · Education · Latest available filing year: 2024 · Primary form: IRS Form 990

  99. Orange Home Inc

    EIN 231261147 · Headquarters: CHARLESTON, SC, USA · Philanthropy, Voluntarism & Grantmaking Foundations · Latest available filing year: 2024 · Primary form: IRS Form 990-PF

  100. Orange Hopes Senior Initiatives

    EIN 815170678 · Headquarters: IRMO, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

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