The American Society for Clinical Investigation Inc

Nonprofit profile at a glance

EIN
520847477
IRS 990 coverage
2010–2025
Forms available
Form 990 2025
Location
Saline, MI, USA
Phone
7342226050
Rating
83
Verdict
STRONG
Rating confidence
Moderate

Official website

Reported finances

Revenue
$8,030,115
Expenses
$7,900,849
Assets
$16,439,989
Liabilities
$911,171

Source: IRS Form 990. Selected filing: tax year 2025. Amounts in USD.

Leadership & pay

24 people listed

Executive titles in this filing

  • STEPHEN CHAN (VICE PRESIDENT, JCI INSIGHT DEPUTY EDITOR)
  • JULIE ANNE BASTARACHE MD (PRESIDENT ELECT)
  • PRISCILLA Y HSUE M D (PRESIDENT)
  • ANNA GREKA MDPHD (IMMEDIATE PAST PRESIDENT)
  • BENJAMIN HUMPHREYS MD PHD (IMMEDIATE PAST PRESIDENT (UNTIL 4/25))
  • JOHN HAWLEY (EXECUTIVE DIRECTOR)

Highest reported compensation

  • JOHN HAWLEY (EXECUTIVE DIRECTOR): $435,805 total reported compensation
  • KAREN GUTH (MANAGING DIRECTOR): $433,864 total reported compensation
  • SARAH C JACKSON (EXECUTIVE EDITOR): $194,911 total reported compensation

Source: IRS Form 990. Selected filing: tax year 2025. Names and roles reflect this filing, not necessarily current officeholders.

Overview

Mission

The american society for clinical investigation seeks to support the scientific efforts, educational needs, and clinical aspirations of physician-scientists to improve the health of all people.

What it reported doing in 2025

This society is organized and operated exclusively for educational and scientific purposes and for no other purpose. The objectives of the corporation, as expressed in the 1908 constitution are: the advancement of medical science; the cultivation of clinical research by the methods of the natural sciences; the correlation of science with the art of medical practice; the encouragement of scientific investigation by the medical practitioner; and the diffusion of a scientific spirit among its members. To this end the society publishes two biomedical journals, the journal of clinical investigation and jci insight, both peer-reviewed biomedical research journals that are available worldwide to members and non members alike, with all research content freely available without restriction of any kind. In 2025, the asci published 499 research articles in the journal of clinical investigation and 522 research articles in jci insight.

Operating model

Revenue model
Earned-program. 81% of the money available for current operations came from fees and other program revenue.
Distribution model
Direct operator. The filing allocates 98% of reported program-service expenses outside its grant, affiliate-payment, and member-benefit lines. This expense classification does not rule out separately announced grant awards.

The verdict

STRONG - A large share of available resources goes toward mission work and the filed numbers largely add up. Expenses are high relative to revenue and total assets are small relative to annual expenses; liquid coverage is unknown.

Rating breakdown

  • Financial Efficiency: 81
  • Transparency & Controls: 87
  • Accountability: 87
  • Sustainability: 41
  • Growth: 100

Detailed rating inputs

Financial Efficiency

  • Mission deployment rate: 92.2%; rating input score 92
  • Program expense ratio: 88.9%; rating input score 89
  • Fundraising efficiency: Limited

Transparency & Controls

  • Consistency checks: 92.9%; rating input score 93; 14th percentile among comparable filings
  • Pay-setting controls: 5 of 6 controls in place; rating input score 83
    • Compensation committee: Pass
    • Independent consultant: Missing
    • Other Form 990s reviewed: Pass
    • Written employment contract: Pass
    • Compensation survey or study: Pass
    • Board or committee approval: Pass
  • Foreign activity oversight: Limited
  • Grant itemization coverage: 92.6%; rating input score 93; 33rd percentile among comparable filings
  • Major donor itemization: Yes; rating input score 100
  • Related-party transparency: Limited

Accountability

  • Independent voting board: 76.9%; rating input score 77; 15th percentile among comparable filings
  • Governance controls: 9 of 9 controls in place; rating input score 100
    • Conflict-of-interest policy: Pass
    • Whistleblower policy: Pass
    • Document-retention policy: Pass
    • CEO compensation review process: Pass
    • Other executive compensation review process: Pass
    • Form 990 shared with the board: Pass
    • Board meeting minutes documented: Pass
    • Audit committee oversight: Pass
    • Independent financial-statement audit: Pass

Sustainability

  • Operating margin: 1.6%; rating input score 32; 32nd percentile among comparable filings
  • Total-asset coverage ratio: 2.08; rating input score 59; 59th percentile among comparable filings
  • Liabilities to assets ratio: 0.06; rating input score 58; 58th percentile among comparable filings
  • Officer compensation ratio: 22.2%; rating input score 13; 13th percentile among comparable filings

Growth

  • Program expense growth: 6.8% per year; rating input score 100; 46th percentile among comparable filings
  • Revenue growth: 5.1% per year; rating input score 100; 38th percentile among comparable filings
  • Asset growth: 4.2% per year; rating input score 100; 28th percentile among comparable filings

Details

  • Where the money goes: 92.2% of revenue deployed · 88.9% of spending went to programs
  • Governance: 10 of 13 board members independent · 9 of 9 filing controls reported
  • Programs: 2 filed program accomplishments · $7M in reported program spending
  • Leadership: top reported pay $436K · 24 people listed · 5 of 6 pay-setting controls reported
  • Highest-paid contractors: 1 contractor listed · $157K reported
  • Consistency: 34 of 35 current checks pass · 1 finding to review
  • Schedules: 6 filed schedules · includes major donors, grants, and executive pay
  • Filing history: 16 filing years from 2010 to 2025
  • Contacts: How to reach this organization
  • Money network: 11 filed money-flow records
  • Related organizations: 1 filed related-organization link
  • Grant readiness: Federal tax and exclusion status, award history, and grant-maker relationships.
  • People: Everyone the filings name, and which of them the filings identify by more than a name.
  • Staff and benefit plans: Retirement and health plans the organization files with the Department of Labor, and the people in them.

Key Signals

Signals prioritize questions for review. They are not findings of misconduct.

  • Moderate — Sustainability: Operating margin scored 32/100.
  • Review — Sustainability: Total-asset coverage ratio scored 59/100.
  • High — Sustainability: Officer compensation ratio scored 13/100.
  • Review — Transparency & Controls: Domestic grant itemization did not reconcile in the filed values.
  • Review — Sustainability: Liabilities to assets ratio scored 58/100.