SMC1A Foundation
Nonprofit profile at a glance
- EIN
- 843406755
- IRS 990-N coverage
- 2025–2025
- Official website data refreshed
- Aug 2026
- Forms available
- Form 990-EZ 2020, Form 990-N 2025
- Location
- San Francisco, CA, US
- Rating confidence
- Limited
- Sector
- Epilepsy
What the e-Postcard reports
- Notice states gross receipts normally $50,000 or less
- Yes
- Termination reported
- No
- Principal officer
- Piret Saagpakk
- Tax period began
- 2025-01-01 00:00:00
- Tax period ended
- 2025-12-31 00:00:00
- Filed website
- smc1a-epilepsy.org
Source: IRS Form 990-N, tax year 2025. These are filed notice facts, not independently verified current operations. The notice does not report exact revenue, expenses, assets, leadership compensation, or governance controls.
Overview
From its website
SMC1A Foundation is a nonprofit organization dedicated to accelerating research and finding a cure for SMC1A-related Developmental and Epileptic Disorder (DEE), a rare X-linked genetic condition that causes developmental impairment and intractable seizures. The foundation builds and sustains an active research pipeline focused on innovative therapeutic approaches and precision medicine. It supports a patient registry, natural history study, and partnerships with platforms like Ciitizen to collect medical records for research. The foundation also fosters a global community through a European chapter led by Daniele Ciampa in Pisa, Italy, and provides resources for families.
IRS classification
Epilepsy (NTEE G54).
Filing
Its tax year 2025 Form 990-N states gross receipts are normally $50,000 or less. The notice does not report termination.
Other filing
A Form 990-EZ for tax year 2020 is also available.
Coverage
Other list screening or federal responsibility records are incomplete in the available data.
Sources: Official website capture · IRS Business Master File · IRS Form 990-N · IRS filing history · Grant-readiness source coverage
The verdict
- The available evidence is not sufficient to produce an overall rating for this filing. This is not a warning sign.
Rating breakdown
Details
- What they do: 2 programs and campaigns described on the official site · 2 operating locations identified
- Postcard: tax year 2025 · gross receipts were within the e-Postcard filing limit
- Contacts: How to reach this organization
- Grant readiness: Federal tax and exclusion status, award history, and grant-maker relationships.
- People: Everyone the filings name, and which of them the filings identify by more than a name.