Provenance Precision Medicine Foundation
Nonprofit profile at a glance
- EIN
- 883109275
- IRS 990-EZ coverage
- 2025–2025
- Forms available
- Form 990 2024, Form 990-EZ 2025, Form 990-N 2023
- Location
- Evanston, IL, USA
- Phone
- 7732553611
- Rating
- 89
- Verdict
- STRONG
- Rating confidence
- Moderate
- Sector
- Fund Raising and/or Fund Distribution
Reported finances
- Revenue
- $75,510
- Expenses
- $207,570
- Assets
- $80,038
- Liabilities
- $9,625
Source: IRS Form 990-EZ. Selected filing: tax year 2025. Amounts in USD.
Leadership & pay
3 people listed
Executive titles in this filing
- Dawn Brooke (Executive Director/Treasurer)
People named in this filing
- Dawn Brooke (Executive Director/Treasurer)
- Saskia Biskup (Secretary)
- David Parker (Chair)
Selected names, not a complete roster or a statement of current roles. Open leadership details for the complete filed list.
Source: IRS Form 990-EZ. Selected filing: tax year 2025. Names and roles reflect this filing, not necessarily current officeholders.
Overview
Mission
The provenance precision medicine foundation is committed to advancing access to innovative cancer treatments-particularly personalized cancer vaccines and other immunotherapies-for patients with advanced disease. Through direct patient support, education, and funding of clinical research, the foundation works to accelerate the availability of these therapies in the united states and help patients navigate options beyond the standard of care.
What it reported doing in 2025
Engaged a consultant to initiate research and strategic planning to support access to cancer vaccine clinical trials in the United States. Two board members also traveled to Germany to meet with researchers and clinicians as part of this effort. These activities are part of the Foundation's ongoing work to expand the availability of innovative immunotherapies for patients with advanced cancer.
Operating model
- Revenue model
- Donor-supported. 100% of the money available for current operations came from contributions and gifts.
- Distribution model
- Grant intermediary. The nonprofit sent 78% of its reported program spending out as grants.
The verdict
STRONG - A large share of available resources goes toward mission work and the filed numbers largely add up. Revenue has declined or grown slowly and expenses are high relative to revenue.
Rating breakdown
- Financial Efficiency: 97
- Transparency & Controls: 100
- Sustainability: 19
- Growth: 0
Detailed rating inputs
Financial Efficiency
- Mission deployment rate: 100%; rating input score 100
- Program expense ratio: 90.7%; rating input score 91
Transparency & Controls
- Consistency checks: 100%; rating input score 100; 51st percentile among comparable filings
- Major donor itemization: Yes; rating input score 100
Sustainability
- Operating margin: -174.9%; rating input score 5; 5th percentile among comparable filings
- Total-asset coverage ratio: 0.39; rating input score 27; 27th percentile among comparable filings
- Liabilities to assets ratio: 0.12; rating input score 14; 14th percentile among comparable filings
- Officer compensation ratio: 0%; rating input score 56; 56th percentile among comparable filings
Growth
- Program expense growth: Limited
- Revenue growth: -115.4% per year; rating input score 0; 2nd percentile among comparable filings
- Asset growth: -87.3% per year; rating input score 0; 2nd percentile among comparable filings
Details
- Where the money goes: 100% of revenue deployed · 90.7% of spending went to programs
- Governance: Filed governance answers
- Accomplishments: 2 filed program accomplishments · $188K in reported program spending
- Leadership: top reported pay $0 · 3 people listed
- Consistency: 8 of 8 current checks pass
- Schedules: 3 filed schedules
- Contacts: How to reach this organization
- Money network: Resolved incoming and outgoing counterparties from filed money flows.
- Grant readiness: Federal tax and exclusion status, award history, and grant-maker relationships.
- People: Everyone the filings name, and which of them the filings identify by more than a name.
Key Signals
Signals prioritize questions for review. They are not findings of misconduct.
- High — Growth: Revenue growth scored 0/100.
- High — Sustainability: Operating margin scored 5/100.
- High — Growth: Asset growth scored 0/100.
- High — Sustainability: Total-asset coverage ratio scored 27/100.
- High — Sustainability: Liabilities to assets ratio scored 14/100.
- Review — Sustainability: Officer compensation ratio scored 56/100.