Nucleate Bio Inc
Nonprofit profile at a glance
- EIN
- 863225994
- IRS 990 coverage
- 2022–2025
- Forms available
- Form 990 2025, Form 990-EZ 2021
- Location
- Brighton, MA, USA
- Phone
- 6178722952
- Rating
- 81
- Verdict
- STRONG
- Rating confidence
- Moderate
- Sector
- Biological & Life Sciences
Reported finances
- Revenue
- $1,759,669
- Expenses
- $1,992,315
- Assets
- $771,653
- Liabilities
- $276,477
Source: IRS Form 990. Selected filing: tax year 2025. Amounts in USD.
Leadership & pay
16 people listed
Executive titles in this filing
- MARISSA PETTIT JONES (PRESIDENT)
People named in this filing
- SOUFIANE ABOULHOUDA (DIRECTOR)
- MARISSA PETTIT JONES (PRESIDENT)
- OLIVER DODD (TREASURER)
Selected names, not a complete roster or a statement of current roles. Open leadership details for the complete filed list.
Source: IRS Form 990. Selected filing: tax year 2025. Names and roles reflect this filing, not necessarily current officeholders.
Overview
Mission
Empower tomorrow's biotech leaders by educating today's acedemic trainees
What it reported doing in 2025
See schedule oactivator program - the goal of the nucleate "activator" program is to provide a rigorous and comprehensive educational experience to future biotech entrepreneurs. Our core curriculum consists of bi-weekly workshops held throughout the spring, and culminates in a final pitch event where teams showcase their companies to a large audience of industry stakeholders.the workshops, created in collaboration with our world-class advisors, are structured to address critical aspects of early-stage life science company formation. Together, they are designed to provide a roadmap for translating and commercializing early-stage technology concepts.each workshop consists of three parts:1) pre-work - teams prepare slides and discussion topics ahead of each workshop, which are circulated to workshop experts in advance. At the end of the program, these slides will form the building blocks of their final 10-15 minute polished pitch deck.2) hands-on feedback - during the 2-hour workshops, teams are paired with experts relevant to their targeted market and/or technology who provide feedback on the materials presented by the teams.3) post-work - after each workshop, teams integrate expert feedback and provide an on topic, one paragraph written summary outlining what was learned and what questions are still outstandin. The post-work summary from each workshop will function as a building block for the final business plan.by the end of the program, teams will leave with a polished pitch deck, written business plan, fundraising strategy, and a network of relevant industry advisors and mentors. This year, our curriculum will be managed and administered through the eduflow platform to create an integrated, uniform, and seamless experience for participants
Operating model
- Revenue model
- Donor-supported. 99% of the money available for current operations came from contributions and gifts.
- Distribution model
- Direct operator. The filing allocates 96% of reported program-service expenses outside its grant, affiliate-payment, and member-benefit lines. This expense classification does not rule out separately announced grant awards.
The verdict
STRONG - A large share of available resources goes toward mission work and the filed numbers largely add up. The filing reports few safeguards for money sent abroad and expenses are high relative to revenue.
Rating breakdown
- Financial Efficiency: 82
- Transparency & Controls: 75
- Accountability: 100
- Sustainability: 21
- Growth: 100
Detailed rating inputs
Financial Efficiency
- Mission deployment rate: 96.4%; rating input score 96
- Program expense ratio: 85.2%; rating input score 85
- Fundraising efficiency: Limited
Transparency & Controls
- Consistency checks: 100%; rating input score 100; 63rd percentile among comparable filings
- Pay-setting controls: Limited
- Foreign activity oversight: 0 of 8 controls in place; rating input score 0
- Claims monitoring procedures: Fail
- Requires narrative reports: Fail
- Conducts field audits: Fail
- May suspend future funding: Fail
- Requires financial reports: Fail
- Conducts site visits: Fail
- Requires grant agreements: Fail
- May require repayment: Fail
- Grant itemization coverage: 100%; rating input score 100; 78th percentile among comparable filings
- Major donor itemization: Yes; rating input score 100
- Related-party transparency: Limited
Accountability
- Independent voting board: 100%; rating input score 100; 64th percentile among comparable filings
- Governance controls: 7 of 7 controls in place; rating input score 100
- Conflict-of-interest policy: Pass
- Whistleblower policy: Pass
- Document-retention policy: Pass
- CEO compensation review process: NotApplicable
- Other executive compensation review process: NotApplicable
- Form 990 shared with the board: Pass
- Board meeting minutes documented: Pass
- Audit committee oversight: Pass
- Independent financial-statement audit: Pass
Sustainability
- Operating margin: -13.2%; rating input score 10; 10th percentile among comparable filings
- Total-asset coverage ratio: 0.39; rating input score 19; 19th percentile among comparable filings
- Liabilities to assets ratio: 0.36; rating input score 17; 17th percentile among comparable filings
- Officer compensation ratio: 0%; rating input score 78; 78th percentile among comparable filings
Growth
- Program expense growth: 13% per year; rating input score 100; 66th percentile among comparable filings
- Revenue growth: 27.7% per year; rating input score 100; 89th percentile among comparable filings
- Asset growth: 20.4% per year; rating input score 100; 79th percentile among comparable filings
Details
- Where the money goes: 96.4% of revenue deployed · 85.2% of spending went to programs
- Governance: 16 of 16 board members independent · 7 of 7 filing controls reported
- Programs: 1 filed program accomplishment · $1.7M in reported program spending
- Leadership: top reported pay $0 · 16 people listed
- Consistency: 32 of 32 current checks pass
- Schedules: 6 filed schedules · includes major donors, foreign activity, and grants
- Filing history: 4 filing years from 2022 to 2025
- Contacts: How to reach this organization
- Money network: 1 filed money-flow record
- Related organizations: 1 filed related-organization link
- Grant readiness: Federal tax and exclusion status, award history, and grant-maker relationships.
- People: Everyone the filings name, and which of them the filings identify by more than a name.
- Staff and benefit plans: Retirement and health plans the organization files with the Department of Labor, and the people in them.
Key Signals
Signals prioritize questions for review. They are not findings of misconduct.
- High — Transparency & Controls: Foreign activity oversight: 8 of 8 not reported.
- High — Sustainability: Operating margin scored 10/100.
- High — Sustainability: Total-asset coverage ratio scored 19/100.
- High — Sustainability: Liabilities to assets ratio scored 17/100.