N-lorem Foundation

Nonprofit profile at a glance

EIN
843288113
IRS 990 coverage
2019–2025
Forms available
Form 990 2025
Location
Carlsbad, CA, USA
Phone
7603788001
Rating
73
Verdict
SUPPORTED
Rating confidence
Moderate
Sector
Birth Defects and Genetic Diseases

Official website

Reported finances

Revenue
$30,807,703
Expenses
$18,339,178
Assets
$22,298,749
Liabilities
$3,196,035

Source: IRS Form 990. Selected filing: tax year 2025. Amounts in USD.

Leadership & pay

24 people listed

Executive titles in this filing

  • STANLEY T CROOKE MD PHD (CHAIR/CEO)

Highest reported compensation

  • SARAH GLASS (COO): $501,818 total reported compensation
  • Julie Douville (VP ASO Disc & Dev): $369,834 total reported compensation
  • LAURY MIGNON (ExDir Clinical Dev): $364,874 total reported compensation

Source: IRS Form 990. Selected filing: tax year 2025. Names and roles reflect this filing, not necessarily current officeholders.

Overview

Mission

N-lorem's mission is creating individual treatments for patients in the united states with nano-rare diseases caused by genetic mutations that affect approximately 30 patients in the world.

What it reported doing in 2025

To provide advanced, experimental rna-targeted medicines, free of charge for life, to patients living with nano-rare diseases.

Operating model

Revenue model
Donor-supported. 99% of the money available for current operations came from contributions and gifts.
Distribution model
Direct operator. The filing allocates 100% of reported program-service expenses outside its grant, affiliate-payment, and member-benefit lines. This expense classification does not rule out separately announced grant awards.
  • Includes noncash contributions: Reported contributions include donated property or goods.

The verdict

SUPPORTED - A large share of total spending goes to programs and the filed numbers largely add up. A relatively small share of available resources goes toward mission work and few specific pay-setting methods are documented in the filing; unanswered boxes are not proof of absence.

Rating breakdown

  • Financial Efficiency: 68
  • Transparency & Controls: 65
  • Accountability: 91
  • Sustainability: 60
  • Growth: 100

Detailed rating inputs

Financial Efficiency

  • Mission deployment rate: 53.9%; rating input score 54
  • Program expense ratio: 89.9%; rating input score 90
  • Fundraising efficiency: $53.79 raised per $1 spent on fundraising; rating input score 75; 75th percentile among comparable filings

Transparency & Controls

  • Consistency checks: 100%; rating input score 100; 64th percentile among comparable filings
  • Pay-setting controls: 0 of 6 controls in place; rating input score 0
    • Compensation committee: Missing
    • Independent consultant: Missing
    • Other Form 990s reviewed: Missing
    • Written employment contract: Missing
    • Compensation survey or study: Missing
    • Board or committee approval: Missing
  • Foreign activity oversight: Limited
  • Grant itemization coverage: Limited
  • Major donor itemization: Yes; rating input score 100
  • Related-party transparency: Limited

Accountability

  • Independent voting board: 93.3%; rating input score 93; 22nd percentile among comparable filings
  • Governance controls: 7 of 8 controls in place; rating input score 88
    • Conflict-of-interest policy: Pass
    • Whistleblower policy: Pass
    • Document-retention policy: Pass
    • CEO compensation review process: NotApplicable
    • Other executive compensation review process: Fail
    • Form 990 shared with the board: Pass
    • Board meeting minutes documented: Pass
    • Audit committee oversight: Pass
    • Independent financial-statement audit: Pass

Sustainability

  • Operating margin: 40.5%; rating input score 89; 89th percentile among comparable filings
  • Total-asset coverage ratio: 1.22; rating input score 35; 35th percentile among comparable filings
  • Liabilities to assets ratio: 0.14; rating input score 59; 59th percentile among comparable filings
  • Officer compensation ratio: 15.1%; rating input score 11; 11th percentile among comparable filings

Growth

  • Program expense growth: 35.8% per year; rating input score 100; 96th percentile among comparable filings
  • Revenue growth: 25.3% per year; rating input score 100; 95th percentile among comparable filings
  • Asset growth: 16.8% per year; rating input score 100; 86th percentile among comparable filings

Details

  • Where the money goes: 53.9% of revenue deployed · 89.9% of spending went to programs
  • Governance: 14 of 15 board members independent · 7 of 8 filing controls reported
  • Programs: 1 filed program accomplishment · $16.5M in reported program spending
  • Leadership: top reported pay $502K · 24 people listed · 0 of 6 pay-setting controls reported
  • Highest-paid contractors: 1 contractor listed · $106K reported
  • Consistency: 30 of 30 current checks pass
  • Schedules: 6 filed schedules · includes major donors and executive pay
  • Filing history: 6 filing years from 2019 to 2025
  • Contacts: How to reach this organization
  • Money network: 9 filed money-flow records
  • Related organizations: Filed and resolved organization relationships.
  • Grant readiness: Federal tax and exclusion status, award history, and grant-maker relationships.
  • People: Everyone the filings name, and which of them the filings identify by more than a name.
  • Staff and benefit plans: Retirement and health plans the organization files with the Department of Labor, and the people in them.

Key Signals

Signals prioritize questions for review. They are not findings of misconduct.

  • Review — Financial Efficiency: Mission deployment rate scored 54/100.
  • High — Transparency & Controls: Pay-setting controls scored 0/100.
  • Review — Accountability: Governance controls: Other executive compensation review process not reported.
  • Moderate — Sustainability: Total-asset coverage ratio scored 35/100.
  • High — Sustainability: Officer compensation ratio scored 11/100.
  • Review — Sustainability: Liabilities to assets ratio scored 59/100.