City of Hope

Legal name: Beckman Research Institute of the City of Hope

Nonprofit profile at a glance

EIN
953432210
IRS 990 coverage
2009–2024
Official website data refreshed
Sep 2026
Forms available
Form 990 2024, Form 990-T 2024
Location
Duarte, CA, USA
Phone
6262564673
Rating
83
Verdict
STRONG
Rating confidence
Moderate
Sector
Cancer Research

Official website

Reported finances

Revenue
$332,532,052
Expenses
$385,146,731
Assets
$2,280,669,212
Liabilities
$1,067,230,062

Source: IRS Form 990. Selected filing: tax year 2024. Amounts in USD.

Leadership & pay

32 people listed

Executive titles in this filing

  • ROBERT W STONE (PRESIDENT & CEO)
  • MARCELLUS R VAN DEN BRINK MD PHD (COHNMC PRESIDENT & CHF PHYS EXEC)

Highest reported compensation

  • ROBERT W STONE (PRESIDENT & CEO): $7,115,860 total reported compensation
  • MARCELLUS R VAN DEN BRINK MD PHD (COHNMC PRESIDENT & CHF PHYS EXEC): $2,570,014 total reported compensation
  • HARLAN ALCON LEVINE (PRES, HLTH INNOVATION & POLICY): $2,496,845 total reported compensation

Source: IRS Form 990. Selected filing: tax year 2024. Names and roles reflect this filing, not necessarily current officeholders.

Overview

Mission

City of Hope is focused on basic and clinical research in cancer, diabetes and other chronic, life-threatening diseases. City of Hope patients benefit from our extraordinary capabilities and leading-edge technology advances such as the application of robotics to remove disease and the use of innovative methods to deliver chemotherapy to treat tumors that would otherwise be unreachable; the use of genetically re-engineered white cells to target and attack a patient’s cancer cells; and the use of advanced imaging techniques to more precisely deliver radiation therapy. Our support also extends to our community through our network of clinical locations. We work with our patients and their families at each step of the journey, providing interdisciplinary supportive services, including psychology, patient education,.

What it reported doing in 2024

Biomedical research and disease investigations, including dna synthesis and cell analysis. Beckman research institute has pioneered scientific breakthroughs resulting in treatments that have improved the lives of patients worldwide. Numerous life-saving drugs use patented technology developed at beckman research institute. These drugs include synthetic human insulin (humulin) for diabetes, the widely used cancer drugs herceptin, rituxan and avastin, and humira for arthritis. Researchers at beckman research institute undertake fundamental investigations in diabetes progression and treatment, immunology and imaging, interfering rnas and HIV treatment, total synthesis of complex and therapeutic natural products, mechanisms of drug action, neurogenesis, stem cell therapy, dna repair and radiation, and the immunobiology of viral infection. They have achieved major advances in recombinant dna technology, monoclonal antibodies, gene therapy, epigenetics, si-rna technology and cancer immunotherapeutics. A department in beckman research institute is dedicated to understanding and developing treatments based on cancer's interaction with the immune system. Other research has identified proteins that may play critical roles in immune response and may lead to new treatment strategies. Another major emphasis for the beckman research institute scientists is personalized research and medicine -- analyzing a patient's unique genetic profile to develop tailored therapies for their specific disease. All of this research is uniquely supported by onsite manufacturing facilities that can test and produce quantities of cell-based, gene-based and molecular therapies. These facilities further serve as resources for medical and scientific research centers nationwide. Beckman research institute scientists serve as faculty members in city of hope's irell & manella graduate school of biological sciences. The graduate school's mission is to train students to be outstanding research scientists in chemical, molecular and cellular biology. The school is accredited by the western association of schools and colleges. Graduates of the program, awarded a doctorate of philosophy in biological sciences, are equipped to address fundamental questions in life sciences and biomedicine for careers in academia, industry and government.

Operating model

Revenue model
Mixed. Its operating money came from several sources; no one source provided a clear majority.
Distribution model
Direct operator. The filing allocates 100% of reported program-service expenses outside its grant, affiliate-payment, and member-benefit lines. This expense classification does not rule out separately announced grant awards.

The verdict

STRONG - A large share of available resources goes toward mission work and the filed numbers largely add up. The filing reports few safeguards for money sent abroad and the filing does not identify recipients for some grant dollars.

Rating breakdown

  • Financial Efficiency: 94
  • Transparency & Controls: 68
  • Accountability: 90
  • Sustainability: 36
  • Growth: 100

Detailed rating inputs

Financial Efficiency

  • Mission deployment rate: 100%; rating input score 100
  • Program expense ratio: 82.6%; rating input score 83
  • Fundraising efficiency: $1,363.61 raised per $1 spent on fundraising; rating input score 97; 97th percentile among comparable filings

Transparency & Controls

  • Consistency checks: 100%; rating input score 100; 68th percentile among comparable filings
  • Pay-setting controls: 6 of 6 controls in place; rating input score 100
    • Compensation committee: Pass
    • Independent consultant: Pass
    • Other Form 990s reviewed: Pass
    • Written employment contract: Pass
    • Compensation survey or study: Pass
    • Board or committee approval: Pass
  • Foreign activity oversight: Scored; rating input score 0
  • Grant itemization coverage: Scored; rating input score 0
  • Major donor itemization: Yes; rating input score 100
  • Related-party transparency: Yes; rating input score 100

Accountability

  • Independent voting board: 90.9%; rating input score 91; 39th percentile among comparable filings
  • Governance controls: 8 of 9 controls in place; rating input score 89
    • Conflict-of-interest policy: Pass
    • Whistleblower policy: Pass
    • Document-retention policy: Pass
    • CEO compensation review process: Pass
    • Other executive compensation review process: Pass
    • Form 990 shared with the board: Fail
    • Board meeting minutes documented: Pass
    • Audit committee oversight: Pass
    • Independent financial-statement audit: Pass

Sustainability

  • Operating margin: -15.8%; rating input score 5; 5th percentile among comparable filings
  • Total-asset coverage ratio: 5.92; rating input score 87; 87th percentile among comparable filings
  • Liabilities to assets ratio: 0.47; rating input score 39; 39th percentile among comparable filings
  • Officer compensation ratio: 3.6%; rating input score 31; 31st percentile among comparable filings

Growth

  • Program expense growth: 1.4% per year; rating input score 100; 12th percentile among comparable filings
  • Revenue growth: 0.6% per year; rating input score 100; 7th percentile among comparable filings
  • Asset growth: 7.8% per year; rating input score 100; 57th percentile among comparable filings

Details

  • What they do: 2 programs and campaigns described on the official site · 1 operating location identified
  • Where the money goes: 100% of revenue deployed · 82.6% of spending went to programs
  • Governance: 10 of 11 board members independent · 8 of 9 filing controls reported
  • Programs: 1 filed program accomplishment · $318.2M in reported program spending
  • Leadership: top reported pay $7.1M · 32 people listed · 6 of 6 pay-setting controls reported
  • Highest-paid contractors: 5 contractors listed · $11.9M reported
  • Consistency: 35 of 35 current checks pass
  • Schedules: 9 filed schedules · includes major donors, foreign activity, executive pay, and related organizations
  • Filing history: 16 filing years from 2009 to 2024
  • Contacts: How to reach this organization
  • Money network: 21 filed money-flow records
  • Related organizations: 11 filed related-organization links
  • Grant readiness: Federal tax and exclusion status, award history, and grant-maker relationships.
  • People: Everyone the filings name, and which of them the filings identify by more than a name.

Key Signals

Signals prioritize questions for review. They are not findings of misconduct.

  • High — Transparency & Controls: Foreign activity oversight scored 0/100.
  • High — Transparency & Controls: Grant itemization coverage scored 0/100.
  • High — Sustainability: Operating margin scored 5/100.
  • Review — Accountability: Governance controls: Form 990 shared with the board not reported.
  • Moderate — Sustainability: Officer compensation ratio scored 31/100.
  • Moderate — Sustainability: Liabilities to assets ratio scored 39/100.