Alzheimer's Drug Discovery Foundation
Nonprofit profile at a glance
- EIN
- 201082179
- IRS 990 coverage
- 2013–2025
- Official website data refreshed
- Sep 2026
- Forms available
- Form 990 2025
- Location
- New York, NY, USA
- Phone
- 212.901.8000
- Rating
- 75
- Verdict
- SUPPORTED
- Rating confidence
- Moderate
- Sector
- Gerontology
Reported finances
- Revenue
- $82,162,763
- Expenses
- $47,597,883
- Assets
- $315,495,637
- Liabilities
- $63,362,218
Source: IRS Form 990. Selected filing: tax year 2025. Amounts in USD.
Leadership & pay
41 people listed
Executive titles in this filing
- MARK ROITHMAYR (CEO)
Highest reported compensation
- HOWARD FILLIT MD (FOUNDING ED & CSO): $1,186,018 total reported compensation
- MARK ROITHMAYR (CEO): $740,169 total reported compensation
- LAURA NISENBAUM (EXEC. DIR., DRUG DEV.): $549,765 total reported compensation
Source: IRS Form 990. Selected filing: tax year 2025. Names and roles reflect this filing, not necessarily current officeholders.
Overview
Mission
To develop the drugs, diagnostics, and prevention strategies needed to stop Alzheimer’s.
What it reported doing in 2025
The alzheimer's drug discovery foundation is dedicated to rapidly accelerating the discovery of drugs to prevent, treat and cure alzheimer's disease and related dementias. The addf is solely focused on funding the development of drugs for alzheimer's, employing a venture philanthropy model to support research in academia and the biotech industry.
Operating model
- Revenue model
- Donor-supported. 81% of the money available for current operations came from contributions and gifts.
- Distribution model
- Grant intermediary. The nonprofit sent 77% of its reported program spending out as grants.
- Includes noncash contributions: Reported contributions include donated property or goods.
The verdict
SUPPORTED - A large share of total spending goes to programs and the filed numbers largely add up. A relatively small share of available resources goes toward mission work and the filing reports few safeguards for money sent abroad.
Rating breakdown
- Financial Efficiency: 60
- Transparency & Controls: 77
- Accountability: 94
- Sustainability: 75
- Growth: 100
Detailed rating inputs
Financial Efficiency
- Mission deployment rate: 51.2%; rating input score 51
- Program expense ratio: 84%; rating input score 84
- Fundraising efficiency: $14.59 raised per $1 spent on fundraising; rating input score 35; 35th percentile among comparable filings
Transparency & Controls
- Consistency checks: 100%; rating input score 100; 66th percentile among comparable filings
- Pay-setting controls: 4 of 6 controls in place; rating input score 67
- Compensation committee: Pass
- Independent consultant: Pass
- Other Form 990s reviewed: Missing
- Written employment contract: Missing
- Compensation survey or study: Pass
- Board or committee approval: Pass
- Foreign activity oversight: 2 of 8 controls in place; rating input score 25
- Claims monitoring procedures: Pass
- Requires narrative reports: Pass
- Conducts field audits: Fail
- May suspend future funding: Fail
- Requires financial reports: Fail
- Conducts site visits: Fail
- Requires grant agreements: Fail
- May require repayment: Fail
- Grant itemization coverage: 100%; rating input score 100; 81st percentile among comparable filings
- Major donor itemization: Yes; rating input score 100
- Related-party transparency: Limited
Accountability
- Independent voting board: 97%; rating input score 97; 30th percentile among comparable filings
- Governance controls: 8 of 9 controls in place; rating input score 89
- Conflict-of-interest policy: Pass
- Whistleblower policy: Pass
- Document-retention policy: Pass
- CEO compensation review process: Pass
- Other executive compensation review process: Fail
- Form 990 shared with the board: Pass
- Board meeting minutes documented: Pass
- Audit committee oversight: Pass
- Independent financial-statement audit: Pass
Sustainability
- Operating margin: 42.1%; rating input score 91; 91st percentile among comparable filings
- Total-asset coverage ratio: 6.63; rating input score 82; 82nd percentile among comparable filings
- Liabilities to assets ratio: 0.2; rating input score 67; 67th percentile among comparable filings
- Officer compensation ratio: 9.2%; rating input score 5; 5th percentile among comparable filings
Growth
- Program expense growth: 15.5% per year; rating input score 100; 84th percentile among comparable filings
- Revenue growth: 15.7% per year; rating input score 100; 88th percentile among comparable filings
- Asset growth: 21.5% per year; rating input score 100; 94th percentile among comparable filings
Details
- What they do: 2 programs and campaigns described on the official site · 2 operating locations identified
- Where the money goes: 51.2% of revenue deployed · 84% of spending went to programs
- Governance: 32 of 33 board members independent · 8 of 9 filing controls reported
- Programs: 1 filed program accomplishment · $40M in reported program spending
- Leadership: top reported pay $1.2M · 41 people listed · 4 of 6 pay-setting controls reported
- Highest-paid contractors: 5 contractors listed · $2M reported
- Consistency: 39 of 39 current checks pass
- Schedules: 9 filed schedules · includes major donors, foreign activity, grants, and executive pay
- Filing history: 12 filing years from 2013 to 2025
- Contacts: How to reach this organization
- Money network: 31 filed money-flow records
- Related organizations: 22 filed related-organization links
- Grant readiness: Federal tax and exclusion status, award history, and grant-maker relationships.
- People: Everyone the filings name, and which of them the filings identify by more than a name.
Key Signals
Signals prioritize questions for review. They are not findings of misconduct.
- Review — Financial Efficiency: Mission deployment rate scored 51/100.
- High — Transparency & Controls: Foreign activity oversight: 6 of 8 not reported.
- Moderate — Financial Efficiency: Fundraising efficiency scored 35/100.
- Review — Accountability: Governance controls: Other executive compensation review process not reported.
- High — Sustainability: Officer compensation ratio scored 5/100.