Alliance Mlc Foundation
Nonprofit profile at a glance
- EIN
- 932663633
- IRS 990-EZ coverage
- 2025–2025
- Forms available
- Form 990-EZ 2025, Form 990-N 2024
- Location
- Middletown, DE, USA
- Phone
- 3109905014
- Rating
- 51
- Verdict
- MIXED
- Rating confidence
- Moderate
- Sector
- Fund Raising and/or Fund Distribution
Reported finances
- Revenue
- $75,415
- Expenses
- $3,611
- Assets
- $72,170
Source: IRS Form 990-EZ. Selected filing: tax year 2025. Amounts in USD.
Leadership & pay
3 people listed
Executive titles in this filing
- CHRISTINA MAROUDA (President)
People named in this filing
- CHRISTINA MAROUDA (President)
- Alexandra Chapleau (OFFICER)
- Stephen Sye (OFFICER)
Selected names, not a complete roster or a statement of current roles. Open leadership details for the complete filed list.
Source: IRS Form 990-EZ. Selected filing: tax year 2025. Names and roles reflect this filing, not necessarily current officeholders.
Overview
Mission
To support families around the globe that are affected by Megalencephalic Leukoencephalopathy with Subcortical Cysts (MLC) and to accelerate MLC research.
What it reported doing in 2025
MLC is an extremely rare genetic brain disorder that consists of about 250 known cases worldwide but it is suspected that there are around 2000 cases including countries with unknown statistics.Alliance MLC was created by a group of determined, action-oriented, resilient and ambitious parents who share the dream that one day every person affected by MLC will have the chance to live a long and healthy life.We are committed to providing ongoing support for our families, as well as accelerating progress of MLC research with the ultimate goal of one day developing a treatment. Research is currently ongoing in various cities globally but before this research goes to the next stage of clinical trials, it is imperative that we have a patient registry up and functional.Alliance MLC, with the support of our MLC Medical Consortium, is establishing an international patient registry along with natural history and impact of disease.
Operating model
- Revenue model
- Cannot be determined from the filing. The filing does not provide enough consistent revenue detail to tell how this nonprofit funds its work.
- Distribution model
- Direct operator. The filing allocates 100% of reported program-service expenses outside its grant, affiliate-payment, and member-benefit lines. This expense classification does not rule out separately announced grant awards.
The verdict
MIXED - The filed numbers largely add up and revenue comfortably covers expenses. A relatively small share of available resources goes toward mission work and a relatively small share of total spending goes to programs.
Rating breakdown
- Financial Efficiency: 14
- Transparency & Controls: 100
- Sustainability: 81
- Growth: NotEnoughData
Detailed rating inputs
Financial Efficiency
- Mission deployment rate: 1.7%; rating input score 2
- Program expense ratio: 35%; rating input score 35
Transparency & Controls
- Consistency checks: 100%; rating input score 100; 51st percentile among comparable filings
- Major donor itemization: Yes; rating input score 100
Sustainability
- Operating margin: 95.2%; rating input score 99; 99th percentile among comparable filings
- Total-asset coverage ratio: 19.99; rating input score 96; 96th percentile among comparable filings
- Liabilities to assets ratio: Limited
- Officer compensation ratio: 0%; rating input score 56; 56th percentile among comparable filings
Growth
- Program expense growth: Limited
- Revenue growth: Limited
- Asset growth: Limited
Details
- Where the money goes: 1.7% of revenue deployed · 35% of spending went to programs
- Governance: Filed governance answers
- Accomplishments: 1 filed program accomplishment · $1K in reported program spending
- Leadership: top reported pay $0 · 3 people listed
- Consistency: 6 of 6 current checks pass
- Schedules: 3 filed schedules
- Contacts: How to reach this organization
- Money network: Resolved incoming and outgoing counterparties from filed money flows.
- Related organizations: Filed and resolved organization relationships.
- Grant readiness: Federal tax and exclusion status, award history, and grant-maker relationships.
- People: Everyone the filings name, and which of them the filings identify by more than a name.
Key Signals
Signals prioritize questions for review. They are not findings of misconduct.
- High — Financial Efficiency: Mission deployment rate scored 2/100.
- Moderate — Financial Efficiency: Program expense ratio scored 35/100.
- Review — Sustainability: Officer compensation ratio scored 56/100.