Advance the Cure
Nonprofit profile at a glance
- EIN
- 850717652
- IRS 990-EZ coverage
- 2020–2025
- Forms available
- Form 990-EZ 2025
- Location
- Knoxville, TN, USA
- Phone
- 8655404004
- Rating
- 89
- Verdict
- STRONG
- Rating confidence
- Moderate
- Sector
- Birth Defects, Genetic Diseases Research
Reported finances
- Revenue
- $57,728
- Expenses
- $47,868
- Assets
- $39,322
Source: IRS Form 990-EZ. Selected filing: tax year 2025. Amounts in USD.
Leadership & pay
3 people listed
Executive titles in this filing
- ROD JACK (PRESIDENT)
People named in this filing
- ROD JACK (PRESIDENT)
- LAURIE ALFORD (TREASURER)
- ANGELA RADER (SECRETARY)
Selected names, not a complete roster or a statement of current roles. Open leadership details for the complete filed list.
Source: IRS Form 990-EZ. Selected filing: tax year 2025. Names and roles reflect this filing, not necessarily current officeholders.
Overview
Mission
Advance the cure's mission is to raise funds dedicated for support, research and the discovery of a cure for cystic fibrosis, while improving and prolonging cf patients lives worldwide.
What it reported doing in 2025
Advance the cure's mission is to raise funds dedicated for support, research, and the discovery of a cure for cystic fibrosis, while improving and prolonging cf patients lives worldwide.
Operating model
- Revenue model
- Mixed. Its operating money came from several sources; no one source provided a clear majority.
- Distribution model
- Grant intermediary. The nonprofit sent 100% of its reported program spending out as grants.
The verdict
STRONG - A large share of available resources goes toward mission work and the filed numbers largely add up. Total assets are small relative to annual expenses; liquid coverage is unknown and reported officer compensation is a large share of total spending, which may reflect staffing concentration.
Rating breakdown
- Financial Efficiency: 83
- Transparency & Controls: 100
- Sustainability: 51
- Growth: 100
Detailed rating inputs
Financial Efficiency
- Mission deployment rate: 76.9%; rating input score 77
- Program expense ratio: 92.5%; rating input score 93
Transparency & Controls
- Consistency checks: 100%; rating input score 100; 51st percentile among comparable filings
- Major donor itemization: Yes; rating input score 100
Sustainability
- Operating margin: 17.1%; rating input score 69; 69th percentile among comparable filings
- Total-asset coverage ratio: 0.82; rating input score 42; 42nd percentile among comparable filings
- Liabilities to assets ratio: Limited
- Officer compensation ratio: 0%; rating input score 56; 56th percentile among comparable filings
Growth
- Program expense growth: 0.5% per year; rating input score 100; 49th percentile among comparable filings
- Revenue growth: 4.1% per year; rating input score 100; 66th percentile among comparable filings
- Asset growth: 15% per year; rating input score 100; 79th percentile among comparable filings
Details
- Where the money goes: 76.9% of revenue deployed · 92.5% of spending went to programs
- Governance: Filed governance answers
- Accomplishments: 1 filed program accomplishment · $44K in reported program spending
- Leadership: top reported pay $0 · 3 people listed
- Consistency: 7 of 7 current checks pass
- Schedules: 4 filed schedules
- Filing history: 6 filing years from 2020 to 2025
- Contacts: How to reach this organization
- Grant readiness: Federal tax and exclusion status, award history, and grant-maker relationships.
- People: Everyone the filings name, and which of them the filings identify by more than a name.
Key Signals
Signals prioritize questions for review. They are not findings of misconduct.
- Moderate — Sustainability: Total-asset coverage ratio scored 42/100.
- Review — Sustainability: Officer compensation ratio scored 56/100.