600 Million Stray Dogs Need You Corporation

What it reported doing in 2025

Science Overview for 2025 and the Global Problem We Seek to Solve1) It is believed by many that the global crisis of homeless companion animal overpopulation, the number one cause of suffering for dogs and cats, increased throughout 2025 as their primary source of food increased: human garbage. Millions of homeless dogs and cats continued to suffer as the cycle of reproduction of the homeless by the homeless repeated generation after generation. To end this suffering, our mission remained science-driven and unprecedented: to end the Number One cause of *continued on Sch O *continued from page 2* suffering and premature death for dogs and cats worldwide -overpopulation - by advancing the development of what will become the first one-dose, edible, permanent-lasting birth control formula capable of safely sterilizing stray dogs and cats without surgery.Recognizing that traditional spay and neuter surgery alone cannot solve this problem worldwide, we continued advancing the development of the Spay and Neuter Cookie as a cruelty-free, scalable, science-based, effective alternative. Building upon prior progress, we continued testing chemicals to produce lifelong sterilization from a single cookie, while our small dedicated team continued advancing this groundbreaking and complex scientific work, despite serious constraints ranging from threats and harassment to insufficient resources and funding. 2) In 2025, we were compelled to spend a substantial amount of effort improving the crucial analysis of 'the follicle count'. Before delving into these specifics, it is important to understand why the follicle count is so important.In short, the follicle count tells us whether our birth-control formula is actually working. Follicles are located in the ovaries, and once a follicle dies (usually with advancing age), it cannot be replaced, and without enough follicles, reproduction cannot take place. This natural condition in humans is referred to as menopause. As our goal is to develop a single-dose, permanent, lasting birth control treatment for dogs and cats, the most important question is: Did our formula permanently shut down the ovary's ability to produce future eggs? The follicle count helps answer that question.Before the follicle count: Researchers often had to rely on indirect clues: Did the animal become pregnant? Or did hormone levels change? Any number of questions. The problem is that these clues can be misleading. The follicle count gives us a more direct answer. By carefully examining treated ovarian tissues and analyzing their follicles, we can determine: How many follicles remain. What types of follicles remain? Whether the treatment damaged only some follicles or nearly all of them, and so on.Why this matters: We are not trying to create a birth control method that works for a few months. We are working to develop something far more ambitious: A safe, inexpensive, edible, one-dose treatment that permanently prevents reproduction - without the need for capture, injections or surgery. To prove that such a treatment truly works, we need evidence that the formula has eliminated, or sufficiently depleted, the viable ovarian reserve. The follicle count is one of the strongest ways to demonstrate that. A robust follicle-count method can help answer questions from: Scientific reviewers, Grant agencies, Regulatory authorities, Veterinary experts, and Potential partners. It provides objective evidence rather than relying on assumptionsIn short: The follicle count is important because it allows us to directly measure whether our one-dose formula has permanently disabled the ovary's capacity to produce fertile eggs that are necessary for becoming pregnant - the central requirement for ending the uncontrolled reproduction in stray dogs and cats.3) Analyzing the Follicle: Our Attempts to Automate Pathology Reporting with Artificial Intelligence. In 2025 we invested significant time in attempting to automate our pathology reporting using A

Financial Efficiency

• Mission deployment rate: 61.1%; rating input score 61
• Program expense ratio: 82.4%; rating input score 82
• Fundraising efficiency: $15.29 raised per $1 spent on fundraising; rating input score 48; 48th percentile among comparable filings

Transparency & Controls

• Consistency checks: 100%; rating input score 100; 63rd percentile among comparable filings
• Pay-setting controls: Limited
• Foreign activity oversight: Scored; rating input score 0
• Grant itemization coverage: Scored; rating input score 0
• Major donor itemization: Yes; rating input score 100
• Related-party transparency: Limited

Accountability

• Independent voting board: 66.7%; rating input score 67; 17th percentile among comparable filings
• Governance controls: 6 of 8 controls in place; rating input score 75
  • Conflict-of-interest policy: Pass
  • Whistleblower policy: Pass
  • Document-retention policy: Pass
  • CEO compensation review process: Pass
  • Other executive compensation review process: NotApplicable
  • Form 990 shared with the board: Pass
  • Board meeting minutes documented: Pass
  • Audit committee oversight: Missing
  • Independent financial-statement audit: Fail

Sustainability

• Operating margin: 30.6%; rating input score 82; 82nd percentile among comparable filings
• Total-asset coverage ratio: 2.26; rating input score 68; 68th percentile among comparable filings
• Liabilities to assets ratio: 0.18; rating input score 27; 27th percentile among comparable filings
• Officer compensation ratio: 8.7%; rating input score 41; 41st percentile among comparable filings

Growth

• Program expense growth: 11.1% per year; rating input score 100; 61st percentile among comparable filings
• Revenue growth: 16.4% per year; rating input score 100; 77th percentile among comparable filings
• Asset growth: 8.4% per year; rating input score 100; 50th percentile among comparable filings