Human Services nonprofits in South Carolina

Human Services nonprofits in South Carolina. Browse 3,008 public nonprofit profiles. Review organization identities, available filing years, and their complete CharitySense profiles.

Location refers to headquarters recorded in public sources, not an organization’s service area. Classification describes its reported category and does not assess its effectiveness.

Nonprofit profiles

  1. Shepherds House Outreach Ministry

    EIN 203431003 · Headquarters: Goose Creek, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  2. Shepherds Table a Sc Eleemos Corp

    EIN 208725196 · Headquarters: CONWAY, SC, USA · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990

  3. Sherwood Forest Neighborhood Association

    EIN 202026558 · Headquarters: Columbia, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  4. Shes on Edge Collective

    EIN 394013389 · Headquarters: Folly Beach, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  5. Shield Ministries

    EIN 208885273 · Headquarters: NORTH CHARLESTON, SC, USA · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990

  6. Shirley S House Inc

    EIN 834298037 · Headquarters: Roebuck, SC, US · Human Services · Latest available filing year: 2021 · Primary form: IRS Form 990-N

  7. Shiwa

    EIN 204972928 · Headquarters: Mount Pleasant, SC, US · Human Services · Latest available filing year: 2008 · Primary form: IRS Form 990-N

  8. Shoes for Kids Inc

    EIN 851229882 · Headquarters: Travelers Rest, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  9. Shoes for Kidz Ministry

    EIN 824035566 · Headquarters: Lake City, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  10. Shoes4water

    EIN 474777163 · Headquarters: Wirges, SC, USA · Human Services · Latest available filing year: 2018 · Primary form: IRS Form 990-EZ

  11. Show Them We Care Foundation

    EIN 710908489 · Headquarters: Columbia, SC, US · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  12. Shwachman-diamond Syndrome Foundation

    EIN 431709945 · Headquarters: VAN WYCK, SC, USA · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990

  13. Sigma Pi Development Group of Greater Aiken

    EIN 872685512 · Headquarters: AIKEN, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  14. Sign N Sealed Services

    EIN 922781571 · Headquarters: Myrtle Beach, SC, US · Human Services · Latest available filing year: 2023 · Primary form: IRS Form 990-N

  15. Silver Star Tent No 4 Etal

    EIN 850720943 · Headquarters: Effingham, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  16. Simple Ministries of Asia

    EIN 463057799 · Headquarters: IRMO, SC, USA · Human Services · Latest available filing year: 2023 · Primary form: IRS Form 990-EZ

  17. Simply Siblings

    EIN 205521909 · Headquarters: Columbia, SC, US · Human Services · Latest available filing year: 2010 · Primary form: IRS Form 990-N

  18. Sims Chapel Sympathy Club

    EIN 274239535 · Headquarters: SPARTANBURG, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  19. Sincerely Bri

    EIN 474832081 · Headquarters: Simpsonville, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  20. Single Parent Institute

    EIN 473580862 · Headquarters: Sumter, SC, US · Human Services · Latest available filing year: 2016 · Primary form: IRS Form 990-N

  21. Singleton Universal Services Inc

    EIN 272335516 · Headquarters: Charleston, SC, US · Human Services · Latest available filing year: 2010 · Primary form: IRS Form 990-N

  22. Sister Summit Foundation Inc

    EIN 473010272 · Headquarters: Mt Pleasant, SC, US · Human Services · Latest available filing year: 2014 · Primary form: IRS Form 990-N

  23. Sisters Empowering Each Other

    EIN 825392899 · Headquarters: COLUMBIA, SC, USA · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-EZ

  24. Sisters Empowering Sisters Inc

    EIN 831068471 · Headquarters: McClellanville, SC, USA · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-EZ

  25. Sisters Encouraging Sisters Ministries

    EIN 461953472 · Headquarters: Columbia, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  26. Sisters Healing and Evolving Inc

    EIN 850812068 · Headquarters: WALTERBORO, SC, US · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  27. Sisters in Need- Caring Connecting Collaborating-sinc3

    EIN 475313769 · Headquarters: Aiken, SC, US · Human Services · Latest available filing year: 2023 · Primary form: IRS Form 990-N

  28. Sisters of Mercy Cdc

    EIN 832175338 · Headquarters: Columbia, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  29. Skibridge Inc

    EIN 862106085 · Headquarters: COLUMBIA, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  30. Sky Kids Incorporated

    EIN 453177806 · Headquarters: Johns Island, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  31. Skyla Strong

    EIN 814846670 · Headquarters: GREER, SC, USA · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990

  32. Sleigh Belles

    EIN 873617734 · Headquarters: Edisto, SC, US · Human Services · Latest available filing year: 2021 · Primary form: IRS Form 990-N

  33. Small Ijose Swanier Foundation Inc

    EIN 833738123 · Headquarters: COLUMBIA, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  34. Small Mind Academy Inc

    EIN 473570851 · Headquarters: Georgetown, SC, USA · Human Services · Latest available filing year: 2017 · Primary form: IRS Form 990-EZ

  35. Small Steps Big Strides Infanttoddler Center

    EIN 832401260 · Headquarters: ORANGEBURG, SC, US · Human Services · Latest available filing year: 2018 · Primary form: IRS Form 990-N

  36. Smith Lane Community Center Inc

    EIN 900953341 · Headquarters: Pageland, SC, US · Human Services · Latest available filing year: 2014 · Primary form: IRS Form 990-N

  37. Smores Kidz

    EIN 822899401 · Headquarters: Denmark, SC, US · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  38. Social Pulse Home Care Agency Inc

    EIN 992892154 · Headquarters: Little River, SC, USA · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990-EZ

  39. Society for Social Change

    EIN 822112230 · Headquarters: Charleston, SC, US · Human Services · Latest available filing year: 2017 · Primary form: IRS Form 990-N

  40. Sohiz Community Outreach

    EIN 334529745 · Headquarters: N Charleston, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  41. Soldiers at Home

    EIN 320530017 · Headquarters: MARION, SC, US · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  42. Soldiers of Hope Inc

    EIN 612216282 · Headquarters: CHARLESTON, SC, USA · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-EZ

  43. Soleful Giving Foundation

    EIN 992279295 · Headquarters: Florence, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  44. Solid Black

    EIN 863339681 · Headquarters: Enoree, SC, US · Human Services · Latest available filing year: 2023 · Primary form: IRS Form 990-N

  45. Solutionsenabled Inc

    EIN 931382153 · Headquarters: Ridgeland, SC, US · Human Services · Latest available filing year: 2023 · Primary form: IRS Form 990-N

  46. Sonshine Club

    EIN 450948731 · Headquarters: SPARTANBURG, SC, USA · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-EZ

  47. Soul of Palestine

    EIN 994699958 · Headquarters: Seneca, SC, USA · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990-EZ

  48. Soul Winner Ministries

    EIN 113793983 · Headquarters: Georgetown, SC, US · Human Services · Latest available filing year: 2014 · Primary form: IRS Form 990-N

  49. Soul2give

    EIN 934494459 · Headquarters: HILTON HEAD ISLAND, SC, USA · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-EZ

  50. South Carolina Association of Pregnancy Care Centers

    EIN 201530986 · Headquarters: Aiken, SC, USA · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990

  51. South Carolina Black Pride Inc

    EIN 264597295 · Headquarters: COLUMBIA, SC, USA · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-EZ

  52. South Carolina Breastfeeding Coalition

    EIN 571007332 · Headquarters: MT PLEASANT, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  53. South Carolina Catholic Engaged Encounter Inc

    EIN 471886702 · Headquarters: SIMPSONVILLE, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  54. South Carolina Chamber Foundation

    EIN 371865869 · Headquarters: COLUMBIA, SC, USA · Human Services · Latest available filing year: 2021 · Primary form: IRS Form 990-EZ

  55. South Carolina Childrens Hospital Collaborative

    EIN 571121266 · Headquarters: Mount Pleasant, SC, USA · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-EZ

  56. South Carolina Corporate Coalition for Community Service

    EIN 460624240 · Headquarters: Columbia, SC, US · Human Services · Latest available filing year: 2019 · Primary form: IRS Form 990-N

  57. South Carolina Crime Victims Council

    EIN 352296291 · Headquarters: Columbia, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  58. South Carolina Dental Relief Fund

    EIN 576030068 · Headquarters: Columbia, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  59. South Carolina Disabilities and Special Needs Foundation

    EIN 570738144 · Headquarters: Cayce, SC, US · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  60. South Carolina Disability Connection

    EIN 465572397 · Headquarters: Lexington, SC, US · Human Services · Latest available filing year: 2013 · Primary form: IRS Form 990-N

  61. South Carolina Friends of Foster Children

    EIN 510508930 · Headquarters: Greenville, SC, US · Human Services · Latest available filing year: 2012 · Primary form: IRS Form 990-N

  62. South Carolina Hispanic Leadership Council

    EIN 020617064 · Headquarters: Irmo, SC, US · Human Services · Latest available filing year: 2021 · Primary form: IRS Form 990-N

  63. South Carolina HIV Council

    EIN 570994526 · Headquarters: COLUMBIA, SC, USA · Human Services · Latest available filing year: 2020 · Primary form: IRS Form 990

  64. South Carolina Indian Affairs Commission

    EIN 571081720 · Headquarters: Conway, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  65. South Carolina Lions Foundation

    EIN 800796488 · Headquarters: COLUMBIA, SC, USA · Human Services · Latest available filing year: 2015 · Primary form: IRS Form 990

  66. South Carolina Multilingual Services Center

    EIN 824580202 · Headquarters: Greer, SC, US · Human Services · Latest available filing year: 2017 · Primary form: IRS Form 990-N

  67. South Carolina Pest ManagementCharitable

    EIN 611755987 · Headquarters: Columbia, SC, USA · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990-EZ

  68. South Carolina Phi Beta Sigma Fraternity Inc

    EIN 611895005 · Headquarters: Simpsonville, SC, US · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  69. South Carolina Public Records Association

    EIN 571034772 · Headquarters: York, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  70. South Carolina Quilts of Valor

    EIN 205100267 · Headquarters: North Charleston, SC, US · Human Services · Latest available filing year: 2013 · Primary form: IRS Form 990-N

  71. South Carolina Respite Coalition

    EIN 571117542 · Headquarters: COLUMBIA, SC, USA · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990

  72. South Carolina Spinal Cord Injury Association

    EIN 570951166 · Headquarters: COLUMBIA, SC, USA · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-EZ

  73. South Carolina Youth Advocate Program

    EIN 341652048 · Headquarters: Columbia, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990

  74. South Strand Support for Students Inc

    EIN 863705635 · Headquarters: Myrtle Beach, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  75. Southcarolina Cap Directors Association Inc

    EIN 710891190 · Headquarters: Beaufort, SC, US · Human Services · Latest available filing year: 2011 · Primary form: IRS Form 990-N

  76. Southeastern Children's Home Inc

    EIN 237061916 · Headquarters: DUNCAN, SC, USA · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990

  77. Southern Bbq Network

    EIN 273279614 · Headquarters: Summerville, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  78. Southern Chic Inc

    EIN 932662485 · Headquarters: Conway, SC, USA · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990-EZ

  79. Southern Sunflower Foundation

    EIN 843165577 · Headquarters: GREER, SC, USA · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990-EZ

  80. Sowing Seeds for Empowerment

    EIN 812949465 · Headquarters: Beaufort, SC, US · Human Services · Latest available filing year: 2016 · Primary form: IRS Form 990-N

  81. Spanish America

    EIN 883639078 · Headquarters: Charleston, SC, USA · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990-EZ

  82. Sparrow Ranch

    EIN 810867564 · Headquarters: YORK, SC, USA · Human Services · Latest available filing year: 2022 · Primary form: IRS Form 990-EZ

  83. Spartanburg County Foster And

    EIN 571100617 · Headquarters: BOILING SPRINGS, SC, US · Human Services · Latest available filing year: 2009 · Primary form: IRS Form 990-N

  84. Spartanburg County Medical Society Alliance

    EIN 570689364 · Headquarters: DRAYTON, SC, USA · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990-EZ

  85. Spartanburg Creative Reuse Art Project

    EIN 931794848 · Headquarters: Lyman, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  86. Spartanburg Jaycees Charities Inc

    EIN 571088413 · Headquarters: Greenville, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  87. Spartanburg Juneteenth Inc

    EIN 812765006 · Headquarters: SPARTANBURG, SC, USA · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990-EZ

  88. Spartanburg Shares

    EIN 471490938 · Headquarters: Spartanburg, SC, US · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  89. Speak Life Inspiration Ministry

    EIN 853103537 · Headquarters: BAMBERG, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  90. Speak Up Magazine

    EIN 271497892 · Headquarters: Rock Hill, SC, USA · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990-EZ

  91. Special Needs and Abilities Family Enpowerment

    EIN 474356813 · Headquarters: CATAWBA, SC, USA · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-PF

  92. Sped Design

    EIN 843482144 · Headquarters: Travelers Rest, SC, US · Human Services · Latest available filing year: 2019 · Primary form: IRS Form 990-N

  93. Spin-single Parents in Need

    EIN 471585353 · Headquarters: Greenville, SC, US · Human Services · Latest available filing year: 2014 · Primary form: IRS Form 990-N

  94. Spirithorse Therapeutic Riding Center

    EIN 453543014 · Headquarters: Ravenel, SC, US · Human Services · Latest available filing year: 2014 · Primary form: IRS Form 990-N

  95. Spiritual Foundation Community Development Corporation

    EIN 204562854 · Headquarters: Orangeburg, SC, US · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990-N

  96. Spiritual Union Association Oakley South Carolina Inc

    EIN 570672540 · Headquarters: MONCKS CORNER, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  97. Spiritually Connected Ministries

    EIN 261871952 · Headquarters: Columbia, SC, US · Human Services · Latest available filing year: 2022 · Primary form: IRS Form 990-N

  98. Spokes Group of Charleston

    EIN 461039583 · Headquarters: Charleston, SC, US · Human Services · Latest available filing year: 2019 · Primary form: IRS Form 990-N

  99. Spreadjoy

    EIN 845097826 · Headquarters: COLUMBIA, SC, US · Human Services · Latest available filing year: 2025 · Primary form: IRS Form 990-N

  100. Springbank Christian Center Dominican Retreat Hous

    EIN 570373409 · Headquarters: Kingstree, SC, USA · Human Services · Latest available filing year: 2024 · Primary form: IRS Form 990

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